On April 25, 2011, Angel Flight accepted its first mission for the Shriners Hospital for Children of Greenville, SC. In the early morning hours, Matt flew to Greenville, NC to pick up the Glisson family and bring them to Greenville, SC. The Glisson’s two year-old son suffered a stroke at birth which caused developmental complications. The Shriner’s Hospital planned to evaluate William for surgery to correct irregularities in the development of his feet. The event was featured on Fox Carolina News.